Isoniazid and hypoglycaemia in a premature infant

Ovali F., Samanci N., Sevinc E., Dagoglu T.

JOURNAL OF PAEDIATRICS AND CHILD HEALTH, vol.40, no.8, pp.490-492, 2004 (SCI-Expanded) identifier identifier identifier


Severe hypoglycaemia requiring more than 20 mg/kg per minute glucose infusion was seen in a premature infant. The infant was born to a woman with active tuberculosis, and she was on prophylactic isoniazid. Discontinuation of isoniazid resulted in prompt recovery of hypoglycaemia. Further pharmacological studies may be needed to establish a cause and effect relationship.