Akademik Veri Yönetim Sistemi
The XII CONGRESS of The WORLD SOCIETY of EMERGENCY SURGERY, Antalya, Türkiye, 21 - 25 Ekim 2025, ss.14-15, (Özet Bildiri)
Objective: Splanchnic venous thrombosis (SVT) is a common complication in necrotizing pancreatitis, contributing to increased morbidity. The role of anticoagulant therapy in the management of SVT remains controversial. This study aims to identify the factors influencing SVT formation and recanalization in patients with necrotizing pancreatitis and to evaluate the efficacy of anticoagulant treatment. Materials and Methods: A retrospective analysis was conducted on 121 patients diagnosed with necrotizing pancreatitis between July-2013 and August-2022. Sociodemographic and clinical characteristics, comorbidities, anticoagulant use, and computed-tomography findings at admission and during follow-ups up to one year were evaluated. Results: SVT was detected in 51 (42.1%) of 121 patients. Among them, 24 (47.1%) had partial occlusion and 27 (52.9%) had total occlusion. Recanalization occurred in 18 (35.3%) of 51 patients. Thrombosis incidence correlated with higher computed tomography severity index (CTSI) scores. Recanalization rates were significantly lower in total occlusions (p < 0.001). Diabetes mellitus was associated with lower recanalization rates (p = 0.019). No significant association was found between therapeutic-dose anticoagulant therapy and thrombosis formation (p = 0.239) or recanalization (p = 0.438). Conclusion: Clinical course of necrotizing pancreatitis is a dynamic and complex process and SVT is strongly associated with both the severity and persistence of inflammation. Recanalization primarily depends on the resolution of inflammation, and therapeutic-dose anticoagulant therapy does not appear to provide significant benefit. Diabetes mellitus negatively affects recanalization outcomes. Total occlusion makes recanalization more difficult. Keywords: Anticoagulation, Diabetes Mellitus, Necrotizing Pancreatitis, Recanalization, Thrombosis