The effect of halofuginone, a specific inhibitor of collagen type 1 synthesis, in the prevention of pancreatic fibrosis in an experimental model of severe hyperstimulation and obstruction pancreatitis

Karatas, Adem; Paksoy, Melih; Erzin, Yusuf; Carkman, Sinan; Gonenc, Murat; Ayan, Fadil; Aydogan, Fatih; Uzun, Hafize; Durak, Haydar

doi:10.1016/j.jss.2008.03.015

The effect of halofuginone, a specific inhibitor of collagen type 1 synthesis, in the prevention of pancreatic fibrosis in an experimental model of severe hyperstimulation and obstruction pancreatitis

Karatas A., Paksoy M., Erzin Y., Carkman S., Gonenc M., Ayan F., ...More

JOURNAL OF SURGICAL RESEARCH, vol.148, no.1, pp.7-12, 2008 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 148 Issue: 1
Publication Date: 2008
Doi Number: 10.1016/j.jss.2008.03.015
Journal Name: JOURNAL OF SURGICAL RESEARCH
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.7-12
Istanbul University Affiliated: Yes

Abstract

Background. The aim of this paper is to assess the effects of halofuginone, a specific inhibitor of synthesis of collagen Type 1, on fibrogenetic process in an experimental model of early pancreatic fibrosis.