Gender disparities in ocular inflammatory disorders.

Sen H. N. , Davis J., Ucar D. , Fox A., Chan C. C. , Goldstein D. A.

Current eye research, vol.40, no.2, pp.146-61, 2015 (Journal Indexed in SCI Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 40 Issue: 2
  • Publication Date: 2015
  • Doi Number: 10.3109/02713683.2014.932388
  • Journal Name: Current eye research
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.146-61


Ocular inflammatory disorders disproportionately affect women, and the majority of affected women are of childbearing age. The role of sex or reproductive hormones has been proposed in many other inflammatory or autoimmune disorders, and findings from non-ocular autoimmune diseases suggest a complex interaction between sex hormones, genetic factors and the immune system. However, despite the age and sex bias, factors that influence this disparity are complicated and unclear. This review aims to evaluate the gender disparities in prevalence, incidence and severity of the most common infectious and non-infectious ocular inflammatory disorders.