Gender disparities in ocular inflammatory disorders.

Sen H. N., Davis J., Ucar D., Fox A., Chan C. C., Goldstein D. A.

Current eye research, cilt.40, sa.2, ss.146-61, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 40 Sayı: 2
  • Basım Tarihi: 2015
  • Doi Numarası: 10.3109/02713683.2014.932388
  • Dergi Adı: Current eye research
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.146-61
  • İstanbul Üniversitesi Adresli: Hayır

Özet

Ocular inflammatory disorders disproportionately affect women, and the majority of affected women are of childbearing age. The role of sex or reproductive hormones has been proposed in many other inflammatory or autoimmune disorders, and findings from non-ocular autoimmune diseases suggest a complex interaction between sex hormones, genetic factors and the immune system. However, despite the age and sex bias, factors that influence this disparity are complicated and unclear. This review aims to evaluate the gender disparities in prevalence, incidence and severity of the most common infectious and non-infectious ocular inflammatory disorders.