Capsule endoscopy (CE) is a noninvasive and easy method for evaluating the gastrointestinal (GI) tract. Since the wireless CE system was first developed, many new technical improvements have been made in order to gain maximum benefit from thisprocedure. However, at this stage, it remains a diagnostic modality, the main indication for its use being obscure GI bleeding. CE is only contraindicated in symptomatic intestinal obstruction. New indications for use and therapeutic options may become possible with the further development of nanotechnologies.