Comparison and efficacy of two different sheep pox vaccines prepared from the Bakirkoy strain against lumpy skin disease in cattle

Uzar S., Sarac F., Gulyaz V., Enul H., YILMAZ H., TURAN N.

CLINICAL AND EXPERIMENTAL VACCINE RESEARCH, vol.11, no.1, pp.1-11, 2022 (ESCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 11 Issue: 1
  • Publication Date: 2022
  • Doi Number: 10.7774/cevr.2022.11.1.1
  • Journal Name: CLINICAL AND EXPERIMENTAL VACCINE RESEARCH
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus
  • Page Numbers: pp.1-11
  • Keywords: Lumpy skin disease, Cattle, Vaccines, MDBK cell, Sheep pox virus, VIRUS, CAPRIPOXVIRUSES, EMERGENCE, ANTIGEN, THREAT
  • Istanbul University Affiliated: No

Abstract

Purpose: Lumpy skin disease (LSD) is a highly contagious and economically important viral infection of cattle, which leads to financial losses in the livestock industry of affected countries. Vaccination is the most effective control measure to prevent the disease. Heterologous sheep pox (SP) vaccine was used against LSD in Turkey. In this research, it was aimed to adapt SP Bakirkoy vaccine strain attenuated in lamb kidney cells to Madin-Darby bovine kidney (MDBK) cells to provide better protection than commercial SP vaccine in cattle.