Akademik Veri Yönetim Sistemi
4. Uluslararası ve 15. Akademik Geriatri Kongresi, İzmir, Türkiye, 14 - 18 Eylül 2022, ss.109, (Tam Metin Bildiri)
Introduction: Frailty is a clinical syndrome characterized with decreased reserve in geriatric practice. Frailty can be closely related with prognosis in cardiovascular diseases. In this study, it was aimed to prospectively evaluate the relationship between short term survival and frailty evaluated with Simplified Fried Frailty Score, which is newly developed by Turkish science people, in elderly patients with heart failure. Methods: 101 consecutive heart failure cases selected from patients aged 65 or above who were hospitilized or admitted to out-patient clinics were included in the study. Demographic properties, history of falling, known chronic diseases, drug history were taken; antropometric properties, hand-grip strenghts (with Jamar hand dynamometry), muscular masses (with BIA), cognitive states (with Mini-Cog and clock drawing tests), nutritional states (with MNA-SF), life quality (with EQ5D), comorbidities (with Charlson comorbidity score), walking and balance (with Tinetti walking and balance score) were determined. To frailty assessment Simplified Fried Frailty Score was used. Absolute muscular mass was adjusted with body mass index (BMI) and threshold values determined from Turkish population were used for low vs normal muscular mass threshold and muscle strenght thresholds. Results: Of 101 patients who were included to the study, 48 was female, 53 was male, and their mean age was 75,8 ± 7.6 years. % 63,4 (n: 64) of patients were frail, %25.7 (n: 26) had malnutrition, and %74,7 (n: 75) had muscular weakness. According to skeletal muscular mass index 110 14-18 Eylül 2022, İzmir (SMMI) %34,1 (n: 82) of patients’ muscular mass was decreased. % 18,8 (n: 19) had confirmed sarcopenia in accordance with EGSWOP2 criteria. % 24,8 (n: 25) of patients had history of falling at least once in the last year. The cases were determined at the median 99 th day (minmax: 6-647 day)and were monitored 136 ± 100 days. In this process 10 cases were deceased, and all were frail. When deceased and survived compared, there was no difference regarding the gender (p=0,869). In logistic regression analysis model which takes survival dependent variable, age, gender, BMI, hand grip strength, having sarcopenia, Tinetti walking and balance scores, Charlson comorbidity score, NT-pro BNP level, MNA-SF and MiniCog scores as a independent variable; frailty was the only factor that significantly effects survival (OR= 0,019; %95 GA: 0,001-0,579; p=0,023). In Kaplan-Meier survival analysis frailty increases the mortality (p=0,010, Fig 1). Conclusion: The results show that physical frailty determined with Simplified Fried Frailty Score is closely associated with short-term mortality in elderly heart failure patients. Keywords: Frailty, Heart Failure, Survival