Common Variants in the ATP-binding Cassette Transporter 1 Gene with Decreased HDL-Cholesterol Levels and Coronary Artery Disease

Catakoglu, Alp; Duman, Belgin; Kurtoglu, Hilal; Ersoz, Melike; Sener, Murat; Celebi, Hueseyin; Cagatay, Penbe; Aytekin, Vedat; Aytekin, Saide

doi:10.1016/j.arcmed.2008.07.008

Common Variants in the ATP-binding Cassette Transporter 1 Gene with Decreased HDL-Cholesterol Levels and Coronary Artery Disease

Catakoglu A. B., Duman B. S., Kurtoglu H., Ersoz M., Sener M., Celebi H., ...Daha Fazla

ARCHIVES OF MEDICAL RESEARCH, cilt.39, sa.8, ss.735-742, 2008 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 39 Sayı: 8
Basım Tarihi: 2008
Doi Numarası: 10.1016/j.arcmed.2008.07.008
Dergi Adı: ARCHIVES OF MEDICAL RESEARCH
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.735-742
İstanbul Üniversitesi Adresli: Hayır

Özet

Background. Our aim was to determine whether the common variants within the coding sequence of ABCA1 gene affects low plasma high-density lipoprotein cholesterol (HDL-C) levels in Turkish patients with coronary artery disease (CAD). The study group was composed of 552 CAD patients, of which 251 had HDL-C levels <= 40 mg/dL, and 301 had HDL-C levels > 40 mg/dL.