Common Variants in the ATP-binding Cassette Transporter 1 Gene with Decreased HDL-Cholesterol Levels and Coronary Artery Disease

Catakoglu, Alp; Duman, Belgin; Kurtoglu, Hilal; Ersoz, Melike; Sener, Murat; Celebi, Hueseyin; Cagatay, Penbe; Aytekin, Vedat; Aytekin, Saide

doi:10.1016/j.arcmed.2008.07.008

Common Variants in the ATP-binding Cassette Transporter 1 Gene with Decreased HDL-Cholesterol Levels and Coronary Artery Disease

Catakoglu A. B., Duman B. S., Kurtoglu H., Ersoz M., Sener M., Celebi H., ...More

ARCHIVES OF MEDICAL RESEARCH, vol.39, no.8, pp.735-742, 2008 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 39 Issue: 8
Publication Date: 2008
Doi Number: 10.1016/j.arcmed.2008.07.008
Journal Name: ARCHIVES OF MEDICAL RESEARCH
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.735-742
Istanbul University Affiliated: No

Abstract

Background. Our aim was to determine whether the common variants within the coding sequence of ABCA1 gene affects low plasma high-density lipoprotein cholesterol (HDL-C) levels in Turkish patients with coronary artery disease (CAD). The study group was composed of 552 CAD patients, of which 251 had HDL-C levels <= 40 mg/dL, and 301 had HDL-C levels > 40 mg/dL.