Akademik Veri Yönetim Sistemi
Annual Congress of the European Association of Nuclear Medicine (EANM'25), Barcelona, İspanya, 4 - 08 Ekim 2025, ss.896, (Özet Bildiri)
Aim/Introduction: An occipital spur is an abnormal bony protrusion that generally develops at the external occipital protuberance (EOP). The EOP has three distinct morphological variants: type I (smooth surface), type II (crest-like shape), and type III (spine-like appearance). Occipital spurs are generally associated with spondylosis or osteoarthritis and may also develop because of repeated trauma. Although incidental and benign, it is important to recognize the entity to differentiate it from metastatic lesions. Materials and Methods: A 31-yearold male, diagnosed with common variable immune deficiency (CVID) and Thrombospondin Type 1 Domain Containing 1 (THSD1) gene mutation which leads to primary lymphedema, was referred to Tc-99m pyrophosphate (PYP) scintigraphy upon suspicious amyloidosis findings in cardiac-MRI. Results: Tc-99m PYP scintigraphy revealed no significant myocardial uptake on either the early or late images and corresponding to a grade 0. However, an incidental finding revealed focal increased uptake in the occipital bone on the whole-body posterior images and SPECT-CT images was showed a focal spine-like hyperostosis which was seen in the occipital protuberance extending in a craniocaudal direction which was confirmed to be an occipital spur (Type III spine form). Conclusion: Tc-99m PYP scintigraphy is a reliable imaging tool primarily used for the noninvasive diagnosis of ATTR cardiac amyloidosis; however incidental uptake in other regions of the body has occasionally been reported. Although only a limited number of cases have been reported in the literature with Tc99m MDP, to our knowledge this is the first reported case demonstrating the visualization of an occipital spur using Tc-99m PYP scintigraphy.