Extreme elevation of serum alpha fetoprotein in decompensated cirrhosis without HCC: an ominous sign

---

Copy For Citation

Senturk H., Cumali R.

INTERNATIONAL JOURNAL OF BIOLOGICAL MARKERS, vol.22, no.1, pp.19-23, 2007 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 22 Issue: 1
• Publication Date: 2007
• Doi Number: 10.5301/jbm.2008.1034
• Journal Name: INTERNATIONAL JOURNAL OF BIOLOGICAL MARKERS
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.19-23
• Istanbul University Affiliated: No

Abstract

Three cases of extreme elevation of serum alpha fetoprotein (>10,000 ng/mL) with decompensated cirrhosis without demonstrable hepatocellular carcinoma are reported. While 2 patients died of liver failure, 1 survived after liver transplantation. Extreme elevation of alpha fetoprotein not associated with hepatocellular carcinoma in liver cirrhosis heralds an ominous prognosis necessitating urgent liver transplantation.