Incidence and Outcomes of Delayed Targeted Therapy After Cytoreductive Nephrectomy for Metastatic Renal-Cell Carcinoma: A Nationwide Cancer Registry Study
CLINICAL GENITOURINARY CANCER, cilt.16, sa.6, 2018 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 16 Sayı: 6
- Basım Tarihi: 2018
- Doi Numarası: 10.1016/j.clgc.2018.08.001
- Dergi Adı: CLINICAL GENITOURINARY CANCER
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Anahtar Kelimeler: Kidney cancer, Surveillance, Systemic therapy, Tyrosine kinase inhibitor, Watchful waiting, ACTIVE SURVEILLANCE, INTERFERON-ALPHA, EFFICACY, WATCH
- İstanbul Üniversitesi Adresli: Evet
Özet
The National Cancer Data Base was analyzed to evaluate the impact of delaying initiation of targeted therapy (TT) for metastatic renal-cell carcinoma. After correction for various clinicopathologic factors, delayed initiation of TT was not associated with worse overall survival. This finding supports a practice that appears to be commonplace clinically, although is seldom reported in the literature.