The response of the canine mammary simple carcinoma and carcinosarcoma cells to 5-aminolaevulinic acid-based photodynamic therapy: An in vitro study

Eskiler G. G., TURNA Ö., Ozkan A. D., BAYKAL A., ÖZTÜRK GÜRGEN H., Erk B., ...More

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY, vol.234, 2022 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 234
  • Publication Date: 2022
  • Doi Number: 10.1016/j.jphotobiol.2022.112509
  • Journal Name: JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Aquatic Science & Fisheries Abstracts (ASFA), BIOSIS, CAB Abstracts, Chemical Abstracts Core, Chimica, EMBASE, MEDLINE, Veterinary Science Database
  • Keywords: Canine mammary gland tumor, Photodynamic therapy, 5-aminolaevulinic acid, Apoptosis, Carcinoma, Carcinosarcoma, BREAST-CANCER, GLAND TUMORS, APOPTOSIS, CLASSIFICATION
  • Istanbul University Affiliated: No

Abstract

Backgrounds: Canine mammary gland tumors (CMGTs) are heterogeneous tumors and share many similar features with human breast cancer. Despite the improvement of current treatment options, new treatment modalities are required to effectively kill tumor cells without general toxicity in the treatment of CMGTs. Photodynamic therapy (PDT) is a promising method for cancer treatment. However, there is a limited study evaluating the therapeutic efficacy of PDT in the treatment of CMGTs.