Vascular endothelial growth factor G+405C polymorphism may contribute to the risk of developing papillary thyroid carcinoma


Bingul I. , Vural P. , Dogru-Abbasoglu S. , Cil E., Uysal M.

JOURNAL OF CLINICAL LABORATORY ANALYSIS, cilt.31, 2017 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 31 Konu: 6
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1002/jcla.22110
  • Dergi Adı: JOURNAL OF CLINICAL LABORATORY ANALYSIS

Özet

BackgroundPapillary thyroid carcinoma (PTC) is the most common endocrine malignancy. Vascular endothelial growth factor (VEGF) is a mediator implicated with cell proliferation, differentiation and migration, and monocyte/macrophage chemotaxis. In present study, we aimed to investigate the relationship between VEGF gene polymorphisms (G+405C, T-460C, and A-2578C) and PTC susceptibility.