Association of CDH1 -160 C -> A and -347 G -> GA polymorphisms and expression of E-cadherin and gastric cancer: A case-control study


AKÇAKAYA A., Unver N., Kiris T. A. , Guzel M. , Akcakaya F. B. , Cakmakoglu B. , ...More

TURKISH JOURNAL OF SURGERY, vol.37, no.1, pp.41-48, 2021 (Journal Indexed in ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 37 Issue: 1
  • Publication Date: 2021
  • Doi Number: 10.47717/turkjsurg.2021.5097
  • Title of Journal : TURKISH JOURNAL OF SURGERY
  • Page Numbers: pp.41-48

Abstract

Objective: The loss of function of the E-cadherin (CDH1) gene with -160 C -> A and -347 G -> GA polymorphisms is regarded as a critical step for gastric cancer. It was aimed to investigate possible association of these polymorphisms and immunoexpression of E-cadherin with gastric cancer.