Prostatic inflammation and obstructive voiding in the adult Noble rat: Impact of the testosterone to estradiol ratio in serum


Bernoulli J., Yatkin E., Konkol Y., Talvitie E., Santti R., Streng T.

PROSTATE, vol.68, no.12, pp.1296-1306, 2008 (SCI-Expanded, Scopus)

  • Publication Type: Article / Article
  • Volume: 68 Issue: 12
  • Publication Date: 2008
  • Doi Number: 10.1002/pros.20791
  • Journal Name: PROSTATE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1296-1306
  • Istanbul University Affiliated: No

Abstract

BACKGROUND. The age-related decline of the testosterone to estradiol (T-to-E-2) ratio in serum is associated with the increased prevalence of prostatic inflammation and lower urinary tract symptoms suggesting obstructive voiding. The impact of the T-to-E-2 ratio on the development and reversal of non-bacterial prostatic inflammation and obstructive voiding was tested in adult Noble rats.