PROSTATE, cilt.68, sa.12, ss.1296-1306, 2008 (SCI-Expanded)
BACKGROUND. The age-related decline of the testosterone to estradiol (T-to-E-2) ratio in serum is associated with the increased prevalence of prostatic inflammation and lower urinary tract symptoms suggesting obstructive voiding. The impact of the T-to-E-2 ratio on the development and reversal of non-bacterial prostatic inflammation and obstructive voiding was tested in adult Noble rats.