Termination of early pregnancies in bitches with aglepristone


Akbas M., Kirsan I.

INDIAN VETERINARY JOURNAL, cilt.84, sa.9, ss.971-973, 2007 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 84 Sayı: 9
  • Basım Tarihi: 2007
  • Dergi Adı: INDIAN VETERINARY JOURNAL
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.971-973
  • İstanbul Üniversitesi Adresli: Evet

Özet

Unwanted pregnancies in the bitch could be terminated in mid-gestation by means of drugs suppressing the secretion or hindering the activation of progesterone. This could be attained either by repeated doses of prostaglandin F-2 alpha or doses of bromocriptin or cabergoline reducing the prolactin level. However, the use of these drugs are limited due to their adverse effects (Cinone et al., 2000). As a progesterone receptor antagonist which could be used during the entire gestation without having its effect, cause direct luteolysis on the corpus luteum in opposition to other drugs administered to terminate unwanted pregnancies, aglepristone is a good alternative for terminating pregnancy in the bitch (Fieni et al., 2001).