Evaluation of IL1B rs1143634 and IL6 rs1800796 Polymorphisms with Autism Spectrum Disorder in the Turkish Children

Pekkoc Uyanik K. C., KALAYCI YİĞİN A., DOĞANGÜN B., SEVEN M.

IMMUNOLOGICAL INVESTIGATIONS, vol.51, no.4, pp.766-777, 2022 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 51 Issue: 4
  • Publication Date: 2022
  • Doi Number: 10.1080/08820139.2020.1870489
  • Journal Name: IMMUNOLOGICAL INVESTIGATIONS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database
  • Page Numbers: pp.766-777
  • Keywords: Autism spectrum disorder, IL1B gene, IL6 gene, polymorphism, real-time PCR
  • Istanbul University Affiliated: No

Abstract

Background: Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder caused by genetic, environmental and immunological factors. It is known that neural development processes are affected by immune functions. The aim of this study is to evaluate the relationship between cytokines IL6 and IL1B gene polymorphisms in ASD.