Neoadjuvant sequential chemoradiotherapy versus radiotherapy alone for treatment of high-risk extremity soft tissue sarcoma: a single-institution experience

Kilic L., Ekenel M. , Karabulut S., Agaoglu F., Darendeliler E.

WSPOLCZESNA ONKOLOGIA-CONTEMPORARY ONCOLOGY, vol.21, no.1, pp.60-65, 2017 (Journal Indexed in ESCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 21 Issue: 1
  • Publication Date: 2017
  • Doi Number: 10.5114/wo.2017.66658
  • Journal Indexes: Emerging Sources Citation Index, Scopus
  • Page Numbers: pp.60-65


Aim of the study: Patients with large and high-grade extremity soft-tissue sarcoma are at significant risk for distant metastasis and sarcoma-related death. There is no randomized trial comparing chemoradiotherapy to radio-therapy in the neoadjuvant setting for high risk extremity soft-tissue sarcoma. The aim of this study is to evaluate the outcomes of patients treated with two different modalities (neoadjuvant sequential chemoradio-therapy vs. radiotherapy alone) in a single center.