Research Information System
Research Journal of Pharmacy and Technology, vol.18, no.4, pp.1789-1794, 2025 (Scopus)
Background/Aim: To demonstrate the antibacterial impact of Sidr honey on Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, and Fusobacterium nucleatum bacteria as major periodontopathogens which are responsible for causing periodontitis. Materials and Methods: Minimum Inhibitory Concentration and Minimum Bactericidal Concentration values are calculated using the serial dilution method, and the measurement of the inhibition zone was conducted using the diffusion method on the Mueller Hinton agar medium. Results: According to the study, there are significant differences between the number of bacterial colony groups that develop against Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, and Fusobacterium nucleatum bacteria on the Minimum Inhibitory Concentration (12.5%) and Minimum Bactericidal Concentration(25%) of Yemen Sidr honey with p-value = 0.000. Similarly, the disc diffusion method for Yemeni honey against Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis and Fusobacterium nucleatumbacteria showed significant differences with a p-value (0.000). Conclusion: According to the findings of the study, Yemen Sidr honey revealed its antibacterial effect in inhibiting and preventing the growth of bacteria causing periodontitis.