Determination of poly(ethylene glycol)-400 in urine by Fourier transform-infrared spectrometry


ERSOY L., ATMACA S. , Saglik S. , IMRE S.

ANALYTICAL COMMUNICATIONS, cilt.33, ss.19-20, 1996 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 33 Konu: 1
  • Basım Tarihi: 1996
  • Doi Numarası: 10.1039/ac9963300019
  • Dergi Adı: ANALYTICAL COMMUNICATIONS
  • Sayfa Sayıları: ss.19-20

Özet

A simple and rapid method for the analysis of poly(ethylene glycol)-400 (PEG-400) (used in the study of intestinal physiology) in human urine is described using Fourier transform-infrared spectrometry, The quantitative measurements were carried out by using the absorbance value of the C-O-C band (wavenumber 1100 cm(-1)). The lower limit of determination of PEG-400 in human urine was 0.8 mg cm(-3), Analytical recovery of PEG-400 added to urine controls was 99.6%, The results of the analyses of one urine sample were compared with those obtained by using high-performance liquid chromatography. Limitations and advantages of the two systems are discussed.