Gemcitabine plus cisplatin versus gemcitabine plus carboplatin as first-line chemotherapy in advanced transitional cell carcinoma of the urothelium: Results of a randomized phase 2 trial


Dogliotti L., Carteni G., Siena S., Bertetto O., Martoni A., Bono A., ...Daha Fazla

EUROPEAN UROLOGY, cilt.52, ss.134-141, 2007 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 52 Konu: 1
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1016/j.eururo.2006.12.029
  • Dergi Adı: EUROPEAN UROLOGY
  • Sayfa Sayıları: ss.134-141

Özet

objectives: This phase 2 randomized study compared the toxicity and assessed the efficacy of gemcitabine-cisplatin (GP) and gemcitabine-carboplatin (GC) in patients with advanced transitional. cell carcinoma of the urothelium (TCC), with the main objective to demonstrate a reduction in toxicity of at least 25% in the GC arm.