Expression of growth factor and chemokine receptors: new insights in the biology of inflammatory breast cancer

CABIOĞLU N., Gong Y., Islam R., Broglio K. R., Sneige N., Sahin A., ...More

ANNALS OF ONCOLOGY, vol.18, no.6, pp.1021-1029, 2007 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 18 Issue: 6
  • Publication Date: 2007
  • Doi Number: 10.1093/annonc/mdm060
  • Journal Name: ANNALS OF ONCOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1021-1029
  • Keywords: CCR7, CXCR4, EGFR, HER2-neu, inflammatory breast cancer, LYMPH-NODE METASTASIS, SQUAMOUS-CELL CARCINOMA, CXCR4 EXPRESSION, COMPETING RISKS, POOR-PROGNOSIS, LUNG-CANCER, CCR7, SURVIVAL, SIGNATURE, P53
  • Istanbul University Affiliated: No

Abstract

Purpose: Recent studies have indicated that expression of chemokine receptors CXCR4 and CCR7 could be an indicator of the metastatic potential of breast cancer. Expression of CXCR4 and CCR7 along with the biomarkers HER2-neu and epidermal growth factor receptor (EGFR) was investigated in inflammatory breast cancer (IBC) to evaluate their prognostic implications.