Investigation of the effect of beta-lactam antibiotics and serum on growth and gene expression in Escherichia coli strain JJ1886

Bozcal Dagdeviren E.

TURKISH JOURNAL OF MEDICAL SCIENCES, vol.48, no.6, pp.1340-1350, 2018 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 48 Issue: 6
  • Publication Date: 2018
  • Doi Number: 10.3906/sag-1803-121
  • Journal Name: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.1340-1350
  • Istanbul University Affiliated: Yes

Abstract

Background/aim: beta-Lactamase-producing Escherichia coli strain JJ1886 is an epidemic clone with high virulence properties. Because this strain can survive in the bloodstream, we aimed here to understand how beta-lactam antibiotics and human serum affect the growth and gene expression of this bacterium.