Evaluation of Agar-Based Medium with Sheep Sera for Testing of Drug Susceptibility of Mycobacterium tuberculosis to Isoniazid, Rifampin, Ethambutol, and Streptomycin


ÇOBAN A. Y. , Uzun M. , BOZDOĞAN B.

JOURNAL OF CLINICAL MICROBIOLOGY, vol.51, no.12, pp.4243-4245, 2013 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 51 Issue: 12
  • Publication Date: 2013
  • Doi Number: 10.1128/jcm.01947-13
  • Title of Journal : JOURNAL OF CLINICAL MICROBIOLOGY
  • Page Numbers: pp.4243-4245

Abstract

The performance of sheep sera instead of sheep blood in agar-based media was investigated for susceptibility testing of Mycobacterium tuberculosis against primary drugs. The levels of agreement between agar-based medium supplemented with sheep sera and the proportion method on Middlebrook 7H11 agar as the reference method for determining susceptibility to isoniazid (INH), rifampin (RIF), ethambutol (EMB), and streptomycin (STR) were 98.4, 98.4, 95.3, and 100%, respectively.