Fused heterocycles: Synthesis of some new imidazopyridines as anti-mycobacterial agents

Oezden Kasimogullari B., Cesur Z.

TURKISH JOURNAL OF CHEMISTRY, vol.31, no.6, pp.817-822, 2007 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 31 Issue: 6
  • Publication Date: 2007
  • Journal Name: TURKISH JOURNAL OF CHEMISTRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.817-822
  • Istanbul University Affiliated: Yes

Abstract

The reaction of semicarbazones bearing an imidazo[ 1,2-a] pyridine ring system with mercaptoacetic acid was investigated. The anti-mycobacterial activity of the compounds thus obtained were evaluated against Mycobacterium tuberculosis H(37)Rv, using rifampin as the standard. Only IVe showed activity at 6.25 mu g mL(-1).