Fused heterocycles: Synthesis of some new imidazopyridines as anti-mycobacterial agents

Oezden Kasimogullari B., Cesur Z.

TURKISH JOURNAL OF CHEMISTRY, cilt.31, sa.6, ss.817-822, 2007 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 31 Sayı: 6
  • Basım Tarihi: 2007
  • Dergi Adı: TURKISH JOURNAL OF CHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.817-822
  • İstanbul Üniversitesi Adresli: Evet

Özet

The reaction of semicarbazones bearing an imidazo[ 1,2-a] pyridine ring system with mercaptoacetic acid was investigated. The anti-mycobacterial activity of the compounds thus obtained were evaluated against Mycobacterium tuberculosis H(37)Rv, using rifampin as the standard. Only IVe showed activity at 6.25 mu g mL(-1).