Copy For Citation
AKKOÇ T., Eifan A. O., Ozdemir C., Yazi D., Yesil O., Bahceciler N. N., ...More
IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY, vol.30, no.1, pp.1-11, 2008 (SCI-Expanded)
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Publication Type:
Article / Article
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Volume:
30
Issue:
1
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Publication Date:
2008
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Doi Number:
10.1080/08923970701812159
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Journal Name:
IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY
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Journal Indexes:
Science Citation Index Expanded (SCI-EXPANDED), Scopus
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Page Numbers:
pp.1-11
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Keywords:
hygiene hypothesis, interferon gamma, murine model of asthma, Mycobacterium vaccae, ovalbumin, pregnancy, ALLERGIC SENSITIZATION, ATOPIC-DERMATITIS, BCG VACCINATION, MURINE MODEL, CHILDREN, ASTHMA, INFLAMMATION, CYTOKINES, OVALBUMIN, DISEASE
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Istanbul University Affiliated:
No
Abstract
Although the development of atopy in the newborn is determined by a multitude of factors, an intense Th1 stimulus early in life could be protective by facilitating a switch away from Th2. Aimed to determine the effect of single Mycobacterium vaccae (M. vaccae) immunization to OVA-sensitized pregnant mice on IL-5 and IFN-gamma secretion from placental lymphocytes and splenocytes of offspring.