IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY, vol.30, no.1, pp.1-11, 2008 (Journal Indexed in SCI)
Article / Article
IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY
Science Citation Index Expanded, Scopus
hygiene hypothesis, interferon gamma, murine model of asthma, Mycobacterium vaccae, ovalbumin, pregnancy, ALLERGIC SENSITIZATION, ATOPIC-DERMATITIS, BCG VACCINATION, MURINE MODEL, CHILDREN, ASTHMA, INFLAMMATION, CYTOKINES, OVALBUMIN, DISEASE
Although the development of atopy in the newborn is determined by a multitude of factors, an intense Th1 stimulus early in life could be protective by facilitating a switch away from Th2. Aimed to determine the effect of single Mycobacterium vaccae (M. vaccae) immunization to OVA-sensitized pregnant mice on IL-5 and IFN-gamma secretion from placental lymphocytes and splenocytes of offspring.