THE PROTECTIVE EFFECT OF AN AQUEOUS EXTRACT FROM SMILAX EXCELSA L. AGAINST CARBON TETRACHLORIDE-INDUCED LIVER INJURY IN RATS

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Ozsoy N., Okyar A., Arda-Pirincci P., Can A., Bolkent Ş., Akev N.

AFRICAN JOURNAL OF TRADITIONAL COMPLEMENTARY AND ALTERNATIVE MEDICINES, cilt.13, sa.3, ss.203-208, 2016 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 13 Sayı: 3
  • Basım Tarihi: 2016
  • Doi Numarası: 10.4314/ajtcam.v13i3.24
  • Dergi Adı: AFRICAN JOURNAL OF TRADITIONAL COMPLEMENTARY AND ALTERNATIVE MEDICINES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED)
  • Sayfa Sayıları: ss.203-208
  • Anahtar Kelimeler: Antioxidant enzymes, carbon tetrachloride, liver injury, Smilax excelsa, hepatoprotective activity, ANTIOXIDANT ACTIVITY, OXIDATIVE DAMAGE, IN-VITRO, AMINOTRANSFERASE
  • İstanbul Üniversitesi Adresli: Evet

Özet

Background: Because reactive oxygen species (ROS) contribute to the pathogenesis of various acute and chronic liver diseases, dietary antioxidants and drugs from herbal origins have been proved to be beneficial as therapeutic agents in reversing hepatotoxicity and oxidative stress. The objective of this study was to investigate the protective effect of an aqueous extract from Smilax excelsa L. Shoots and leaves against acute CCl4-induced liver injury as well as the changes in antioxidative defense system in female wistar albino rats.