Goztepe Tip Dergisi, cilt.23, sa.1, ss.10-14, 2008 (Scopus)
The aim of this study to identify clinical and laboratory findings of children with metabolic syndrome as the metabolic syndrome is becomig an important health problem in our population This study was conducted in the Outpatient Clinics of Pediatrics and Pediatric Endocrinology in Sişli Etfal Training and Research Hospital. A total of 52 patients attended for obesity, hypertension and dislipidemia from January 2006 to January 2007 were included. Clinical and laboratory findings were evaluated. Partcipants were divided into two groups according to NCEP ATP III criteria for metabolic syndrome [MS(+) group n:29 & MS(-) group n:23]. There were 26 girls and 26 boys with an age range of 0 to 14 years. 86% of participants were obese and 60% of obese patients had metabolic syndrome. Although not statistically significant, family history of stroke and gestational diabetes mellitus were encountered more frequently in the MS(+) group compared to MS(-) group. CRP levels were not different, but ferritin and fibrinogen levels were higher in MS(+) group than in MS(-) group (p=0.038 and p=0.001 respectively). Additional to known risk factors relative risk for metabolic syndrome was 6.2 for children with a family history of stroke . Insuin resistance and metabolic syndrome has been a health problem threatening children. Our results should be supported with larger population based studies.