The role of FDG-PET/CT in differentiated thyroid cancer patients with negative iodine-131 whole-body scan and elevated anti-Tg level


Asa S., AKSOY S. Y., Vatankulu B., Aliyev A., Uslu L., OZHAN M., ...More

ANNALS OF NUCLEAR MEDICINE, vol.28, no.10, pp.970-979, 2014 (SCI-Expanded, Scopus)

  • Publication Type: Article / Article
  • Volume: 28 Issue: 10
  • Publication Date: 2014
  • Doi Number: 10.1007/s12149-014-0897-7
  • Journal Name: ANNALS OF NUCLEAR MEDICINE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.970-979
  • Istanbul University Affiliated: Yes

Abstract

In the follow-up of differentiated thyroid cancer (DTC) after a successful total-near total thyroidectomy and I-131 ablation therapy, anti-thyroglobulin antibodies (anti-Tg) may be persistently or progressively increased in the patients with an undetectable serum thyroglobulin (Tg) level. In these cases, further investigation was performed to search for recurrence/metastases. The aim of our study was clarifying the role of FDG-PET/CT in detecting recurrence/metastasis in patients with DTC with negative serum Tg and elevated anti-Tg level.