Remembering the Basics: A Patient with Sickle Cell Disease and Proteinuria

Ozbalak E. P. , Mirioglu S., Sahin E., Ozluk Y. , Ucar A. R. , Yazici H. , et al.

TURKISH JOURNAL OF NEPHROLOGY, cilt.28, ss.154-156, 2019 (ESCI İndekslerine Giren Dergi) identifier

  • Cilt numarası: 28 Konu: 2
  • Basım Tarihi: 2019
  • Doi Numarası: 10.5152/turkjnephrol.2019.3198
  • Sayfa Sayısı: ss.154-156


Patients with sickle cell disease (SCD) tend to develop many renal abnormalities, including concentration defect, renal papillary necrosis, and glomerulopathy that often presents with proteinuria. We report a case of a patient who presented with sickle cell crisis and proteinuria. A diagnosis of SCD glomerulopathy was confirmed with renal biopsy. Treatment with angiotensin-converting enzyme inhibitor was initiated, and proteinuria rapidly reduced to 0.27 g/day. It is crucial for a clinician to recognize this important complication and take necessary precautions to delay progression to end-stage renal disease.