Gingival Inflammation and Interleukin-1 beta and Tumor Necrosis Factor-Alpha Levels in Gingival Crevicular Fluid During the Menstrual Cycle

Baser Ü., Cekici A., Tanrikulu-Kucuk S., Kantarci A., Ademoglu E., Yalcin F.

JOURNAL OF PERIODONTOLOGY, vol.80, no.12, pp.1983-1990, 2009 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 80 Issue: 12
  • Publication Date: 2009
  • Doi Number: 10.1902/jop.2009.090076
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1983-1990
  • Keywords: Gingivitis, inflammation, interleukin-1beta, menstrual cycle, progesterone, tumor necrosis factor-alpha, HUMAN PERIPHERAL MONOCYTES, SEX-HORMONES, LUTEAL-PHASE, PROGESTERONE, EXPRESSION, RECEPTORS
  • Istanbul University Affiliated: Yes


Background: Hormonal changes during puberty, pregnancy, and menopause may impact periodontal tissues by altering the host response. There are only a few studies that examined gingival changes during the menstrual cycle. This longitudinal and prospective study aims to investigate clinical and laboratory markers of gingival inflammation in women at different phases during their menstrual cycles.