ENDOCRINE JOURNAL, cilt.47, sa.4, ss.471-473, 2000 (SCI-Expanded)
It is well known that growth hormone (GH) therapy is associated with increased risk of development of malignant tumors, especially leukemia. In the case presented, growth hormone treatment was initiated in a 25-year-old patient with hypopituitarism. After 4 months of therapy with thrice a week injections of rhGH, acute It was thought that no clearcut evidence existed to establish a relationship between the growth hormone treatment and development of acute leukemia.