Effect and Safety of Granulocyte Transfusions in Pediatric Patients With Febrile Neutropenia or Defective Granulocyte Functions

Atay, Didem; Ozturk, Gulyuz; Akcay, Arzu; Yanasik, MELEK; Anak, Sema; Devecioglu, Ömer

doi:10.1097/mph.0b013e31821ffdf1

Effect and Safety of Granulocyte Transfusions in Pediatric Patients With Febrile Neutropenia or Defective Granulocyte Functions

Atay D., Ozturk G., Akcay A., Yanasik M., Anak S., Devecioglu O.

JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, cilt.33, sa.6, 2011 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 33 Sayı: 6
Basım Tarihi: 2011
Doi Numarası: 10.1097/mph.0b013e31821ffdf1
Dergi Adı: JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
İstanbul Üniversitesi Adresli: Evet

Özet

Background: Despite the introduction of new broad-spectrum antibiotics and antifungal therapies over the past decade, infections remains the most frequent cause of death in patients with neutropenia. The aim of this study is to assess the effect and safety of granulocyte transfusions (GTX) for the treatment of severe life-threatening infections in pediatric patients with febrile neutropenia or defective granulocyte functions.