Vascular endothelial growth factor polymorphisms increase the risk of developing Graves' disease


Vural P., Baki M., Dogru-Abbasoglu S., OZDERYA A., KARADAG B., Uysal M.

INTERNATIONAL IMMUNOPHARMACOLOGY, vol.14, no.2, pp.133-137, 2012 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 14 Issue: 2
  • Publication Date: 2012
  • Doi Number: 10.1016/j.intimp.2012.06.018
  • Journal Name: INTERNATIONAL IMMUNOPHARMACOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.133-137
  • Istanbul University Affiliated: Yes

Abstract

Background: Graves' disease (GD) is a consequence of genetic and environmental factors. Vascular endothelial growth factor (VEGF) is a strong angiogenic and mitogenic factor, which plays a key role in lymphocyte infiltration, and hypervascularization in the thyroid gland of patients with GD.