Whole Exome Sequencing in Early-onset Systemic Lupus Erythematosus

Batu, Ezgi; KOŞUKCU, CAN; Taskiran, Ekim; Sahin, Sezgin; AKMAN, SEMA; Sozeri, Betul; Unsal, Erbil; BİLGİNER, YELDA; Kasapcopur, Özgür; ALİKAŞİFOĞLU, MEHMET; ÖZEN, SEZA

doi:10.3899/jrheum.171358

Whole Exome Sequencing in Early-onset Systemic Lupus Erythematosus

Batu E. D., KOŞUKCU C., Taskiran E., Sahin S., AKMAN S., Sozeri B., ...More

JOURNAL OF RHEUMATOLOGY, vol.45, no.12, pp.1671-1679, 2018 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 45 Issue: 12
Publication Date: 2018
Doi Number: 10.3899/jrheum.171358
Journal Name: JOURNAL OF RHEUMATOLOGY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.1671-1679
Istanbul University Affiliated: Yes

Abstract

Objective. Systemic lupus erythematosus (SLE) is a multisystem autoimmune disorder. Early-onset, familial, and/or syndromic SLE may reveal monogenic pathologies. The aim of this study was to examine genetic associations in patients with early-onset or familial SLE.