Synchronization Analysis In Epileptic EEG Signals Via State Transfer Networks Based On Visibility Graph Technique


Olamat A., ÖZEL P., AKAN A.

INTERNATIONAL JOURNAL OF NEURAL SYSTEMS, vol.32, no.02, 2022 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 32 Issue: 02
  • Publication Date: 2022
  • Doi Number: 10.1142/s0129065721500416
  • Journal Name: INTERNATIONAL JOURNAL OF NEURAL SYSTEMS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, PASCAL, Applied Science & Technology Source, Biotechnology Research Abstracts, Compendex, Computer & Applied Sciences, EMBASE, INSPEC, MEDLINE
  • Keywords: Epilepsy, ictal, motif, network, synchronization, visibility graph, GENERALIZED SYNCHRONIZATION, FUNCTIONAL CONNECTIVITY, DIAGNOSIS, LIKELIHOOD, METHODOLOGY
  • Istanbul University Affiliated: No

Abstract

Epilepsy is a persistent and recurring neurological condition in a community of brain neurons that results from sudden and abnormal electrical discharges. This paper introduces a new form of assessment and interpretation of the changes in electroencephalography (EEG) recordings from different brain regions in epilepsy disorders based on graph analysis and statistical rescale range analysis. In this study, two different states of epilepsy EEG data (preictal and ictal phases), obtained from 17 subjects (18 channels each), were analyzed by a new method called state transfer network (STN). The analysis performed by STN yields a network metric called motifs, which are averaged over all channels and subjects in terms of their persistence level in the network. The results showed an increase of overall motif persistence during the ictal over the preictal phase, reflecting the synchronization increase during the seizure phase (ictal). An evaluation of intermotif cross-correlation indicated a definite manifestation of such synchronization. Moreover, these findings are compared with several other well-known methods such as synchronization likelihood (SL), visibility graph similarity (VGS), and global field synchronization (GFS). It is hinted that the STN method is in good agreement with approaches in the literature and more efficient. The most significant contribution of this research is introducing a novel nonlinear analysis technique of generalized synchronization. The STN method can be used for classifying epileptic seizures based on the synchronization changes between multichannel data.