Prenatal diagnosis and outcome of unilateral multicystic kidney


Turkyilmaz G. , Cetin B. , Erturk E. , Sivrikoz T. , Kalelioglu I. , Has R. , ...More

JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 2021 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume:
  • Publication Date: 2021
  • Doi Number: 10.1080/01443615.2020.1845631
  • Title of Journal : JOURNAL OF OBSTETRICS AND GYNAECOLOGY

Abstract

We reviewed the records of 144 patients. The mean gestational age at first US diagnosis was 27.5 +/- 4.3 weeks. An anomaly of the contralateral kidney was detected in 25% of cases. An extrarenal anomaly was detected in 13.8%. Karyotype analysis was performed in 16.6% of cases and revealed trisomy 18 in 2 cases with extrarenal defects. Karyotype analysis was normal in all the patients who had isolated multicystic dysplastic kidney (MCDK). The diagnostic accuracy of prenatal ultrasound was 92.2%. Contralateral kidney anomaly was detected 33.9% of patients, and half of these were vesicoureteral reflux. Antihypertensive therapy was required in 2.6% of cases. Nephrectomy was performed in 8%, and partial or total involution of MCDK was achieved in 33.9% of patients. MCDK can be accurately diagnosed by prenatal sonography, and prognosis depends on extrarenal and contralateral renal abnormalities. In isolated cases, require of surgery is rare, and serial follow-up is suggested to determine involution. Impact statement