Effect of ACSL4 gene polymorphism (rs7886473) on metabolic syndrome and lipid levels

Vurgun E., Diker I. Y., Coban N., Geyik F., Guven G., Unaltuna N.

CUKUROVA MEDICAL JOURNAL, vol.43, pp.151-157, 2018 (ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 43
  • Publication Date: 2018
  • Doi Number: 10.17826/cumj.407589
  • Journal Name: CUKUROVA MEDICAL JOURNAL
  • Journal Indexes: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Page Numbers: pp.151-157
  • Keywords: ACSL4, SNP, lipids, triglyceride, metabolic syndrome, ACYL-COA SYNTHETASE, FATTY-ACID-METABOLISM, INSULIN-RESISTANCE, LIVER FAT, CARDIOVASCULAR-DISEASE, RAT, MEN, SUPPRESSION, INHIBITION, EXPRESSION
  • Istanbul University Affiliated: Yes

Abstract

Purpose: Acyl-CoA synthetase long-chain family member 4 (ACSL4) is thought to be related with obesity and metabolic syndrome via lipid metabolism. We aimed to investigate the effect of the single nucleotide polymorphism (SNP) rs7886473, which is a common intron variant of ACSL4 gene on metabolic syndrome and lipids in Turkish society.