Dose-related effects of recombinant human interleukin-10 on hypoxia-induced skeletal muscle injury in immature rats

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Ozturk K., Demir B., Oke R., Durmaz H.

JOURNAL OF ORTHOPAEDIC SCIENCE, vol.11, no.6, pp.620-625, 2006 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 11 Issue: 6
• Publication Date: 2006
• Doi Number: 10.1007/s00776-006-1063-4
• Journal Name: JOURNAL OF ORTHOPAEDIC SCIENCE
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.620-625
• Istanbul University Affiliated: No

Abstract

Background. The role of cytokines in the pathogenesis of skeletal muscle injury in patients with hypoxia and inflammation remains unclear. The aim of the present study was to determine the dose-related effects of recombinant human interleukin-10 (rhIL-10) on hypoxia-induced skeletal muscle injury in immature rats.