The role of midkine in the inflammatory process and its correlation with other inflammatory markers in renal transplant recipients


Uzun S. , Kaya B., Celik K., Behlul A., Ozkan O., Kuvvet M., ...Daha Fazla

INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS, cilt.39, ss.277-281, 2016 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 39 Konu: 6
  • Basım Tarihi: 2016
  • Doi Numarası: 10.5301/ijao.5000510
  • Dergi Adı: INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS
  • Sayfa Sayıları: ss.277-281

Özet

Background: Midkine (MK), which is expressed in the proximal tubular epithelial cells of the kidney, is thought to have a role in the pathophysiology of inflammation-related renal diseases. Both immunological and nonimmunological mechanisms may affect renal functions negatively during the early and late post-transplantation periods. We aimed in our study to evaluate the relationship of MK with clinical findings and inflammatory markers, including high sensitivity C-reactive protein (hs-CRP), interleukin (IL-6) and tumor necrosis factor (TNF-alpha) in the pretransplant and post-transplant period.