The role of midkine in the inflammatory process and its correlation with other inflammatory markers in renal transplant recipients.
The International journal of artificial organs, cilt.39, sa.6, ss.277-81, 2016 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 39 Sayı: 6
- Basım Tarihi: 2016
- Doi Numarası: 10.5301/ijao.5000510
- Dergi Adı: The International journal of artificial organs
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.277-81
- İstanbul Üniversitesi Adresli: Evet
Özet
Background: Midkine (MK), which is expressed in the proximal tubular epithelial cells of the kidney, is thought to have a role in the pathophysiology of inflammation-related renal diseases. Both immunological and nonimmunological mechanisms may affect renal functions negatively during the early and late post-transplantation periods. We aimed in our study to evaluate the relationship of MK with clinical findings and inflammatory markers, including high sensitivity C-reactive protein (hs-CRP), interleukin (IL-6) and tumor necrosis factor (TNF-alpha) in the pretransplant and post-transplant period.