Instantaneous Wave-Free Ratio: Novel Adenosine-Free Method to Assess Intracoronary Physiology


Creative Commons License

Cimci M., Degrauwe S., Roffi M., Musayeb Y., KARADAĞ B., Iglesias J. F.

TURK KARDIYOLOJI DERNEGI ARSIVI-ARCHIVES OF THE TURKISH SOCIETY OF CARDIOLOGY, cilt.51, sa.1, ss.56-62, 2023 (ESCI) identifier identifier identifier identifier

Özet

Fractional flow reserve assessment was accepted as a crucial strategy in stable patients under-going coronary angiography without prior noninvasive evaluation in the presence of borderline lesions and in patients with multivessel coronary artery disease. Instantaneous wave-free ratio, measured during a specific diastolic interval, emerged as a nonhyperemic pressure ratio. Due to its advantages such as not requiring a vasodilating agent, rapidity of procedure, pullback phe-nomena for the assessment of individual stenosis in tandem lesions or diffusely infiltrated vessels, and virtual percutaneous coronary intervention which allows the assessment and justification 'of' optimal coronary revascularization, instantaneous wave-free ratio became a valuable option in the field of coronary physiology. This review aims to address coronary physiological concept with fractional flow reserve and emergence of instantaneous wave-free ratio through corner-stone studies as well as the use of instantaneous wave-free ratio in different clinical scenarios.