Role of Mesenchymal Stem Cells Transfected With Vascular Endothelial Growth Factor in Maintaining Renal Structure and Function in Rats with Unilateral Ureteral Obstruction


Ozbek E. , Adas G., Otunctemur A., DURUKSU G., Koc B., Polat E. C. , ...Daha Fazla

EXPERIMENTAL AND CLINICAL TRANSPLANTATION, cilt.13, ss.262-272, 2015 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 13 Konu: 3
  • Basım Tarihi: 2015
  • Doi Numarası: 10.6002/ect.2014.0080
  • Dergi Adı: EXPERIMENTAL AND CLINICAL TRANSPLANTATION
  • Sayfa Sayıları: ss.262-272

Özet

Objectives: Mesenchymal stem cells hold promise for renal disease treatment. Vascular endothelial growth factor may heal tubule-interstitial fibrosis in unilateral ureteral obstruction by inhibiting epithelial-mesenchymal transition. We investigated the protective effect of vascular endothelial growth factor in transfected mesenchymal stem cells in unilateral ureteral obstruction-induced renal injury in rats.