Plasma concentrations of soluble cytokine receptors in euthymic bipolar patients with and without subsyndromal symptoms


CETIN T., Guloksuz S., Cetin E. A. , Gazioglu S. B. , Deniz G. , Oral E. T. , ...More

BMC PSYCHIATRY, vol.12, 2012 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 12
  • Publication Date: 2012
  • Doi Number: 10.1186/1471-244x-12-158
  • Title of Journal : BMC PSYCHIATRY

Abstract

Background: Current evidence suggests that high concentrations of pro-inflammatory markers are associated with bipolar disorder characterized by severe impairment during inter-episodic periods, reduced treatment response and persistent subsyndromal symptoms. We tested whether persistent subsyndromal symptoms in euthymic bipolar patients were associated with markers of an ongoing chronic pro-inflammatory process.