MTHFR C677T and A1298C Gene Polymorphisms in Human Kidney Cancer Tissues

Pence H. H., Caykara B., ALsaadoni H., Otunctemur A., Pence S.

ISTANBUL MEDICAL JOURNAL, vol.20, no.5, pp.408-412, 2019 (ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 20 Issue: 5
  • Publication Date: 2019
  • Doi Number: 10.4274/imj.galenos.2019.88709
  • Journal Name: ISTANBUL MEDICAL JOURNAL
  • Journal Indexes: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Page Numbers: pp.408-412
  • Istanbul University Affiliated: Yes

Abstract

Introduction: The potential effect of 5,10-methylenetetrahydrofolate reductase (MTHFR) on DNA methylation, DNA repair and DNA synthesis has made MTHFR a cancer-inducing gene. In this study, we aimed to evaluate C677T and A1298C gene polymorphisms in kidney cancer.