MTHFR C677T and A1298C Gene Polymorphisms in Human Kidney Cancer Tissues

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Pence H. H., Caykara B., ALsaadoni H., Otunctemur A., Pence S.

ISTANBUL MEDICAL JOURNAL, cilt.20, sa.5, ss.408-412, 2019 (ESCI)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 20 Sayı: 5
• Basım Tarihi: 2019
• Doi Numarası: 10.4274/imj.galenos.2019.88709
• Dergi Adı: ISTANBUL MEDICAL JOURNAL
• Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
• Sayfa Sayıları: ss.408-412
• İstanbul Üniversitesi Adresli: Evet

Özet

Introduction: The potential effect of 5,10-methylenetetrahydrofolate reductase (MTHFR) on DNA methylation, DNA repair and DNA synthesis has made MTHFR a cancer-inducing gene. In this study, we aimed to evaluate C677T and A1298C gene polymorphisms in kidney cancer.