Endobronchial intratumoral chemotherapy (EITC) followed by surgery in early non-small cell lung cancer with polypoid growth,causing erroneous impression of advanced disease


Celikoglu S. I., Celikoglu F., Goldberg E. P.

LUNG CANCER, cilt.54, sa.3, ss.339-346, 2006 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 54 Sayı: 3
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1016/j.lungcan.2006.09.004
  • Dergi Adı: LUNG CANCER
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.339-346
  • İstanbul Üniversitesi Adresli: Evet

Özet

Background: Seventeen patients with (MO) non-small cell lung cancer (NSCLC) without distant metastasis were treated by preoperative endobronchial intratumoral chemotherapy (EITC) followed by surgery. Preoperative intratumoral. chemotherapy was performed for the purpose of either reducing the extent of resection or increasing operability. Clinically, in the preliminary diagnostic bronchoscopic examination, the tumor was located in the main stem bronchus closer than 2 cm to the carina [T3] in 12 patients, or at the level of carina or bulging towards the trachea [T4] in 5 patients. In this series of patients, the tumors were originally inoperable due to the inability to achieve a negative margin by standard pneumonectomy techniques. However, EITC rendered resection possible.