Improving local control with breast-conserving therapy - A 27-year single-institution experience


CABIOĞLU N., Hunt K., Buchholz T., Mirza N., Singletary S., Kuerer H., ...More

CANCER, vol.104, no.1, pp.20-29, 2005 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 104 Issue: 1
  • Publication Date: 2005
  • Doi Number: 10.1002/cncr.21121
  • Journal Name: CANCER
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.20-29
  • Keywords: breast-conserving surgery, local recurrence, chemotherapy, hormonal therapy, invasive breast carcinoma, margins, RANDOMIZED CLINICAL-TRIAL, COMPARING TOTAL MASTECTOMY, SURGICAL ADJUVANT BREAST, 20-YEAR FOLLOW-UP, CONSERVATION THERAPY, TUMOR RECURRENCE, STAGE-II, RADIATION-THERAPY, NEOADJUVANT CHEMOTHERAPY, POSTMENOPAUSAL WOMEN
  • Istanbul University Affiliated: No

Abstract

BACKGROUND. The risk of ipsilateral breast tumor recurrence (IBTR) after breast-conserving therapy (BCT) is associated with treatment and tumor-related variables, such as surgical margin status and the use of systemic therapy, and these variables have changed over time. Correspondingly, the authors of the current study hypothesized that the contemporary multidisciplinary management of breast carcinoma would lead to an improvement in IBTR rates after BCT.