Protective effects of onion (Allium cepa) extract against doxorubicin-induced hepatotoxicity in rats

Mete, Rafet; Oran, Mustafa; Topcu, Birol; Oznur, Meltem; Seber, Erdogan; GEDİKBAŞI, Asuman; Yetisyigit, Tarkan

doi:10.1177/0748233713504807

Protective effects of onion (Allium cepa) extract against doxorubicin-induced hepatotoxicity in rats

Atıf İçin Kopyala

Mete R., Oran M., Topcu B., Oznur M., Seber E. S. , GEDİKBAŞI A. , ...Daha Fazla

TOXICOLOGY AND INDUSTRIAL HEALTH, cilt.32, ss.551-557, 2016 (SCI İndekslerine Giren Dergi)

Cilt numarası: 32 Konu: 3
Basım Tarihi: 2016
Doi Numarası: 10.1177/0748233713504807
Dergi Adı: TOXICOLOGY AND INDUSTRIAL HEALTH
Sayfa Sayıları: ss.551-557

Özet

Background/aim: Doxorubicin (DOX) is a widely used and potent chemotherapeutic agent. However, serious dose-limiting toxicity through generation of free oxygen radicals is a commonly encountered clinical problem. The aim of the current study was to assess the protective role of onion (Allium cepa) extract (ACE) against DOX-induced hepatotoxicity in rats.