No Activating Mutations of FSH Receptor in Four Children with Ovarian Juvenile Granulosa Cell Tumors and the Association of These Tumors with Central Precocious Puberty

Bas F., Pescovitz O. H., Steinmetz R.

JOURNAL OF PEDIATRIC AND ADOLESCENT GYNECOLOGY, cilt.22, sa.3, ss.173-179, 2009 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 22 Sayı: 3
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1016/j.jpag.2008.10.003
  • Dergi Adı: JOURNAL OF PEDIATRIC AND ADOLESCENT GYNECOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.173-179
  • Anahtar Kelimeler: Activating mutation, Follicle-stimulating hormone receptor, Central precocious puberty, Children, Granulosa cell tumor, FOLLICLE-STIMULATING-HORMONE, BINDING-SITES, GONADOTROPIN, GENE, FAILURE, PSEUDOPUBERTY, ADOLESCENTS, NEOPLASMS, CLONING, WOMEN
  • İstanbul Üniversitesi Adresli: Evet

Özet

Study Objective: The stimulation of the follicle-stimulating hormone receptor (FSHR) by circulating FSH or some activating mutations of the FSHR may play a causal role in the development of granulosa cell tumors of ovaries.