Synthesis of new triazolyl-N,N-dialkyldithiocarbamates as antifungal agents

Ozkirimli S., Apak T., Kiraz M., Yegenoglu Y.

ARCHIVES OF PHARMACAL RESEARCH, cilt.28, sa.11, ss.1213-1218, 2005 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 28 Sayı: 11
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1007/bf02978200
  • Dergi Adı: ARCHIVES OF PHARMACAL RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1213-1218
  • İstanbul Üniversitesi Adresli: Hayır

Özet

N,N-Dialkylditihiocarbamate derivatives have been well known as broad-range fungicides. In this study, the triazole derivatives of ten new N,N-disubstituted dithiocarbamates (3a-j) were synthesized and their structures were identified by spectral and elemental analysis. Results of the antifungal activity studies showed that some of the compounds tested were active against M. canis, M. gypseum, and T rubrum at the concentration of 12.5 mu g/mL when clotrimazol was used as a standard.