Synthesis of new triazolyl-N,N-dialkyldithiocarbamates as antifungal agents


Ozkirimli S., Apak T., Kiraz M., Yegenoglu Y.

ARCHIVES OF PHARMACAL RESEARCH, cilt.28, ss.1213-1218, 2005 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 28 Konu: 11
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1007/bf02978200
  • Dergi Adı: ARCHIVES OF PHARMACAL RESEARCH
  • Sayfa Sayıları: ss.1213-1218

Özet

N,N-Dialkylditihiocarbamate derivatives have been well known as broad-range fungicides. In this study, the triazole derivatives of ten new N,N-disubstituted dithiocarbamates (3a-j) were synthesized and their structures were identified by spectral and elemental analysis. Results of the antifungal activity studies showed that some of the compounds tested were active against M. canis, M. gypseum, and T rubrum at the concentration of 12.5 mu g/mL when clotrimazol was used as a standard.