Akademik Veri Yönetim Sistemi
ANNALS OF CLINICAL AND ANALYTICAL MEDICINE, sa.1, ss.60-64, 2023 (ESCI)
Aim: In this study, we aimed to investigate the success of conservative treatment in patients with relevant laboratory findings and early-stage spondylodiscitis.Material and Methods: A total of 79 patients (conservative group 38 patients and 41 patients in the surgery group) with early stage spondylodiscitis were included in this study. These patients were divided into two groups as follows: the conservative treatment group included patients in whom conservative treatment was successful, and the surgical treatment group, consisting of patients who underwent surgery due to refractory pain and poor laboratory findings that did not improve despite conservative treatment. Patients underwent laboratory tests twice: first at their initial presentation (initial); then, after antibiotic treatment (end-of-treatment). Laboratory parameters used were C-reactive protein (CRP), white blood count (WBC), platelet count (PLT), erythrocyte sedimentation rate (ESR), neutrophil count, lymphocyte count, monocyte count, NLR, PLR, and MLR ratios.Results: No significant differences were noted between groups in terms of gender, age, and stage. The initial CRP, WBC, neutrophil count, monocyte and platelet were significantly higher in conservative group than in the surgical group. However, there were no significant differences between the groups in the initial ESR, lymphocyte count, NLR, PLR and MLR. The end-of-treatment ESR, WBC, platelet, monocyte, PLR and MLR were significantly higher in the surgical group than in the conservative group. However, there was no significant difference between the groups in the end-of-treatment CRP, neutrophil count, lymphocyte count, NLR. Discussion: Surgery may be considered in patients with spondylodiscitis, when ESR, WBC, platelet, monocyte, PLR, and MLR do not improve with conservative treatment.